Lilly breaks ground in Pennsylvania's Lehigh Valley on a $3.5 billion site to make next-generation obesity medicines, the latest of 10 new U.S. sites since 2020

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Facility will manufacture injectable medicines, including retatrutide Site will create 850 high-wage jobs and 2,000 construction jobs INDIANAPOLIS, Nov. 12, 2026 /PRNewswire/ --…

INDIANAPOLIS, Nov. 12, 2026 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) today broke ground on a $3.5 billion manufacturing facility in Pennsylvania's Lehigh Valley. The site is one of 10 new U.S. manufacturing sites announced since 2020 and one of four among them dedicated to injectable medicines and devices. Part of the company's $50 billion push to expand medicine production in the U.S., the Lehigh Valley site will add capacity for the next generation of obesity treatments, including retatrutide, a first-in-class investigational GIP, GLP-1 and glucagon triple hormone receptor agonist.

David A. Ricks, Lilly Chair and CEO: "Obesity is one of the biggest health challenges of our time, and the science to treat it is moving quickly. Retatrutide is one of several next-generation medicines we're developing that could help millions more people living with obesity, type 2 diabetes, or both. This $3.5 billion investment means we'll be able to make these medicines in Pennsylvania for people here at home and around the world."

Supporting community in the Lehigh ValleyAs part of its community commitment, Lilly and the Upper Macungie Township Community Fund are working together on an anticipated new community initiative at the Upper Macungie Community Center. Lilly will provide up to $1 million over five years to the Upper Macungie Township Community Fund to support an initiative to develop a new quality-of-life program for Lehigh Valley families, with a focus on nutrition and healthy living, fresh food access, health resources, and community programming.

Creating careers in advanced manufacturingLilly is currently hiring in the Lehigh Valley and expects the new facility to create 850 high-wage jobs like engineers, scientists, operations personnel, and lab technicians – along with approximately 2,000 construction jobs as the site is built and brought online.

Pennsylvania Governor Josh Shapiro: "Today marks another historic milestone in Pennsylvania's thriving life sciences…

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